With the use of years and the variation of insects and mites, it is currently difficult to directly kill insects and mites with low content of abamectin alone. The more effect is to reduce the activity capacity, and it must be used in conjunction with compounds with different mechanisms of action Synergistic. Phosphothiazide can inhibit the synthesis of root-knot nematode acetylcholinesterase, and has a dual mechanism of contact and systemic action. The combination of the two has a better control effect on cucumber root-knot nematode.